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Project Number: | I01BX000799-09 |
| Title: | Molecular Control of Gut Permeability in Trauma |
| Principal Investigator: | Mack H Wu |
| Location: | Tampa, FL |
| Congressional District Code: | 14 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2019 - December 2022 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$768,300 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary Systemic inflammation and multiple organ failure associated with trauma are a major cause of mortality and morbidity in American soldiers and veterans. Intestinal barrier dysfunction plays an important role in the development of posttraumatic complications such as sepsis by providing the major site for diffusion of toxins, allergens and bacterial translocation to the circulation. Despite the well- recognized importance of gut dysfunction in the pathogenesis of posttraumatic compl... |