Funded Project Details - FY2021
|Title:|| ATP-Citrate Lyase As A Novel Metabolic Target for Osteoarthritis|
Ru Liu Bryan
||San Diego, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| October 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Aging and obesity are the major risk factors for development of osteoarthritis (OA), the most common form of arthritis. Veterans are at high risk of developing OA, because over 12.4 millions veterans are age 65 or older, and nearly 80% of veterans are obese. For veterans and others, developing effective disease-modifying therapy for OA is a major unmet medical need. As OA progresses, failure of the synovial joint organ frequently develops, with degeneration of articular cartilage as a core disea...
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