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Funded Project Details - FY2021




Project Number:

I01BX001506-05A1
Title: Mechanisms of Interferon-alpha Neurotoxicity
Principal Investigator:

William R. Tyor

Location: Decatur, GA
Congressional District Code: 4
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$865,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Worldwide there are over 35 million individuals living with HIV. As many as 50% of these HIV-infected individuals will develop HIV associated neurocognitive disorders (HAND), despite combined antiretroviral therapy (cART). Yet, since the advent of cART the incidence of HIV associated dementia, the most severe form of HAND, has diminished and represents less than 5% of HAND in countries like the US where cART is available. Therefore, mild forms of HAND, such as Asymptomatic Neurocognitive Impairm...



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