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Funded Project Details - FY2021




Project Number:

I01BX004045-01A2
Title: Investigation of therapeutic potential of exogenous ubiquitin following myocardial ischemia/reperfusion injury
Principal Investigator:

Krishna Singh

Location: Mountain Home, TN
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2024
FY 2021 Funding Amount: $87,059
Total Award Amount
(all years):
$1,333,585
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Ischemic heart disease (IHD) is a leading cause of death among veterans. Myocardial infarction (MI) is a serious outcome of IHD, and is generally attributable to the detrimental effects of myocardial ischemia/reperfusion (I/R) injury. Cardiac inflammation and extracellular matrix deposition (scar formation) are essential events in the cardiac remodeling post-MI. Therapeutic approaches targeting these events may hold promise for patients with MI. This proposal investigates the therapeutic potenti...



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