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Funded Project Details - FY2021

Project Number:

Title: Ocular Sequelae and Intervention in a Rat Model of Blast Overpressure Polytrauma
Principal Investigator:

Steven J. Fliesler

Location: Buffalo, NY
Congressional District Code: 26
Research Service: Biomedical Laboratory R&D
Project Period: January 2019 - December 2022
FY 2021 Funding Amount: $218,462
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Military personnel are frequently exposed to blast-induced shock waves (acoustic blast overpressure, ABO), with intensities sufficient to cause polytrauma, of which traumatic brain injury (TBI) is a common component. Relatively little is known about the structural or functional effects on the retina per se induced by ABO exposure, which initially may be occult and not manifest significantly until weeks to months post-blast. This project focuses on providing an understanding of the etiology and t...

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