Funded Project Details - FY2021
|Title:|| Rotavirus: Studies of the Effectors and Mechanisms of Heterotypic Humoral Immunity in Human Intestinal Epithelial Cells|
Harry B. Greenberg
||Palo Alto, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2019 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Rotaviruses (RVs) are the most important cause of severe diarrhea in young children worldwide. These viruses also cause diarrheal disease in healthy adults, the elderly, and the immune compromised. RV replicates primarily in the mature villous tip cells of the small intestine. RVs infect most mammals in a host-specific fashion; in general, RV strains that cause infection in one mammal do not cause disease in another species. Natural RV infection and live attenuated vaccination effectively induce...
Questions about the R&D website? Email the Web Team
Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.