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Funded Project Details - FY2021

Project Number:

Title: Mechanism of Quinolone Resistance
Principal Investigator:

Neil Osheroff

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $292,810
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Gonorrhea, which is caused by Neisseria gonorrhoeae, is a sexually transmitted disease that currently is categorized by the Centers for Disease Control and Prevention as one of the four “urgent level” drug-resistant threats to the United States. The disease is prevalent in active Military and rates appear to be elevated in Veteran populations. Although quinolones were used routinely to treat gonorrhea starting in 1993, their use as front-line therapy was discontinued in 2006 due to the high inci...

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