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Funded Project Details - FY2021

Project Number:

Title: Dissecting the Role of Inflammation in Smoking and Aging Associated Lung Cancers
Principal Investigator:

James DeGregori

Location: Denver, CO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $238,873
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Tobacco is the leading cause of lung cancer, and is associated with both increased mutation occurrence and dramatic alterations in lung tissue structure and function. Furthermore, about 15% of lung cancers in the U.S. are not associated with smoking, and primarily occur in old age, which is also associated with substantial disruptions in lung structure and function. We do not understand how these changes in lung tissue landscapes impact lung cancer development. A history of smoking is prevalent...

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