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Funded Project Details - FY2021

Project Number:

Title: Advanced Preclinical Testing of a Broad-Spectrum Antiparasitic Quinolones for Veteran Health
Principal Investigator:

Joseph ("Stone") Doggett

Location: Portland, OR
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $155,785
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


VA scientists have discovered antiparasitic quinolones that are highly effective against malaria and toxoplasmosis. Malaria is a potentially fatal infection that is a deployment hazard for veterans. The many veterans who have HIV or who undergo hematopoietic stem cell or solid organ transplant are at risk of developing Toxoplasma encephalitis when they are immunosuppressed. Current treatments for malaria and prophylaxis for malaria are limited by the spread of drug resistance. Medicines for toxo...

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