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Funded Project Details - FY2021




Project Number:

I01BX004344-01A1
Title: Neuroprotection after TBI
Principal Investigator:

Raghu Vemuganti

Location: Madison, WI
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $260,094
Total Award Amount
(all years):
$1,063,454
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Traumatic brain injury (TBI) is one of the leading causes of disability in service personnel and veterans. The effects of TBI in surviving veterans can often be seen for decades after the initial injury. Oxidative stress and endoplasmic reticulum (ER) stress that starts within hours and continues for days are known promoters of neuronal death that lead to long-term neurological deficits after TBI. Importantly oxidative stress and ER stress potentiate each other and act synergistically. Hence, th...



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