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Funded Project Details - FY2021




Project Number:

I01BX004352-01A1
Title: Influence of APOE genotypes on blood brain barrier transport of DHA by mfsd2a in Alzheimer's Disease
Principal Investigator:

Laila Abdullah

Location: Tampa, FL
Congressional District Code: 14
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $185,724
Total Award Amount
(all years):
$856,968
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Over 200,000 US Veterans are suffering from Alzheimer's disease (AD) and this figure is expected to increase dramatically in the next few decades due to a higher prevalence of traumatic brain injury (TBI) and post- traumatic stress disorder (PTSD) that are risk factors of AD among soldiers returning from Iraq and Afghanistan wars. The apolipoprotein E (APOE) ε4 allele is the most prevalent genetic risk factor for AD, representing 60% of AD subjects in the general population. The apoE protein is a...



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