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Project Number: | IK2BX004360-01A1 |
| Title: | Translational Research Career Development: Overcoming Resistance to Radiotherapy |
| Principal Investigator: | Vinita Takiar |
| Location: | Cincinnati, OH |
| Congressional District Code: | 1 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2019 - March 2024 |
| FY 2021 Funding Amount: | $301,376 |
| Total Award Amount (all years): |
$1,448,418 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Head and neck cancer (HNC) is the sixth most common malignancy worldwide, diagnosed twice as frequently in veterans. Radiation therapy (RT) is an important component of cancer treatment; however, its efficacy is limited by radioresistance, with the cancer sometimes returning within the treated area. Resistance to RT is, at least in part, mediated by adaptive signaling events induced by treatment. However, we do not yet understand the pathways used by cells to evade the cellular damage caused by... |