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Funded Project Details - FY2021




Project Number:

IK2BX003865-01A2
Title: Therapeutic Potential of Targeted Mucosal Heme Oxygenase-1 in Colitis
Principal Investigator:

Joseph Onyiah

Location: Denver, CO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: January 2019 - December 2023
FY 2021 Funding Amount: $329,259
Total Award Amount
(all years):
$1,662,155
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Disruptions in the complex balance between inflammatory and homeostatic signaling in the intestinal mucosa can result in diseases such as inflammatory bowel disease (IBD). From this perspective, there is significant interest in identifying endogenous homeostatic pathways in the intestinal mucosa. Targeted activation of these mucosal pathways may restore homeostasis and at the same time avoid the risks of systemic immunosuppression which is frequently utilized for control of IBD. Heme oxygenase-1...



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