Office of Research & Development |
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Project Number: | I01CX001076-05A1 |
Title: | Fecal Microbiota Transplant in Veterans with Cirrhosis |
Principal Investigator: | Jasmohan S Bajaj |
Location: | Richmond, VA |
Congressional District Code: | 3 |
Research Service: | Clinical Science R&D |
Project Period: | April 2019 - March 2023 |
FY 2021 Funding Amount: | $675,844 |
Total Award Amount (all years): |
$2,078,576 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Liver cirrhosis is a major cause of morbidity and mortality in Veterans, primarily due to complications such as ascites and hepatic encephalopathy (HE). HE is linked with a systemic pro-inflammatory milieu propagated by an impaired intestinal barrier and gut dysbiosis. Despite maximal therapy (lactulose/rifaximin), a significant proportion of Veterans have HE that continues to recur, which is a major burden on their caregivers and VHA system. We have recently published a small randomized trial o... |