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Project Number: | I01CX001076-05A1 |
| Title: | Fecal Microbiota Transplant in Veterans with Cirrhosis |
| Principal Investigator: | Jasmohan S Bajaj |
| Location: | Richmond, VA |
| Congressional District Code: | 3 |
| Research Service: | Clinical Science R&D |
| Project Period: | April 2019 - March 2023 |
| FY 2021 Funding Amount: | $675,844 |
| Total Award Amount (all years): |
$2,078,576 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Liver cirrhosis is a major cause of morbidity and mortality in Veterans, primarily due to complications such as ascites and hepatic encephalopathy (HE). HE is linked with a systemic pro-inflammatory milieu propagated by an impaired intestinal barrier and gut dysbiosis. Despite maximal therapy (lactulose/rifaximin), a significant proportion of Veterans have HE that continues to recur, which is a major burden on their caregivers and VHA system. We have recently published a small randomized trial o... |