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Funded Project Details - FY2021

Project Number:

Title: Cerebral arterial compliance, blood flow, and cognition in Veterans with diabetes
Principal Investigator:

Katherine Bangen

Location: San Diego, CA
Congressional District Code: 52
Research Service: Clinical Science R&D
Project Period: October 2019 - March 2024
FY 2021 Funding Amount: $180,556
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Type 2 diabetes mellitus (T2DM), which is highly prevalent among Veterans, increases the risk of cognitive impairment and dementia, including Alzheimer’s disease (AD). We have shown that T2DM—even during midlife—is associated with steeper cognitive decline, reduced cerebral blood flow (CBF) in regions that are predilection sites for AD pathology, and greater neuropathologic changes at autopsy (Bangen et al., 2013; Bangen et al., 2016; Bangen et al., in prep). Identifying individuals who are most...

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