Office of Research & Development |
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Project Number: | I01CX001783-01A1 |
Title: | Investigating the Neural Basis of Shame and Guilt in Veterans with Posttraumatic Stress Disorder |
Principal Investigator: | Rajendra A. Morey |
Location: | Durham, NC |
Congressional District Code: | 1 |
Research Service: | Clinical Science R&D |
Project Period: | April 2019 - March 2023 |
FY 2021 Funding Amount: | $163,516 |
Total Award Amount (all years): |
$675,164 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: ABSTRACT Abnormally regulated fear and threat perception are widely regarded as the core patho- physiological process in posttraumatic stress disorder (PTSD). As a result, associative fear learning models have dominated research on the neuroscience of PTSD. However, shame, guilt, and moral injury, rather than fear, are dominant cognitive processes among individuals with PTSD, which often develops following military combat trauma. Very little is known about how PTSD affects the brain circuits ass... |