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Funded Project Details - FY2021

Project Number:

Title: Corticospinal control of spinal reflex plasticity
Principal Investigator:

Jonathan Wolpaw

Location: Albany, NY
Congressional District Code: 20
Research Service: Clinical Science R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $164,905
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Spinal cord injury (SCI), traumatic brain injury, stroke, multiple sclerosis, and other chronic disorders produce abnormal reflexes that impair locomotion, reach-and-grasp, and other motor functions for millions of Americans, including many Veterans. New treatments are urgently needed. Operant conditioning protocols can change spinal reflexes in rats, mice, monkeys, and people. These protocols, which are non-invasive in humans, can target beneficial plasticity to a specific reflex pathway. The r...

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