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Funded Project Details - FY2021

Project Number:

Title: Preventing levodopa induced dyskinesia in Parkinson’s Disease with Statins
Principal Investigator:

Kathryn A. Chung

Location: Portland, OR
Congressional District Code: 3
Research Service: Clinical Science R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $152,839
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The purpose of this project is to determine whether HMG-CoA reductase inhibitors (statins) will inhibit the progression of levodopa (LD) induced dyskinesia in Parkinson disease (PD) given that rodent and primate models have carefully demonstrated this. LD is the most important medication that Veterans with PD will take to control their symptoms and has remained so since its discovery in the 1960s. Unfortunately, early recognition of the benefits of LD against the stiffness, slowness and tremor o...

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