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Project Number: | I01RX002626-01A2 |
| Title: | SCI Consortium Study: Neural Stem Cell Transplantation for Cervical Spinal Cord Injury |
| Principal Investigator: | John H Brock |
| Location: | San Diego, CA |
| Congressional District Code: | 52 |
| Research Service: | Rehabilitation R&D |
| Project Period: | May 2019 - April 2024 |
| FY 2021 Funding Amount: | $205,360 |
| Total Award Amount (all years): |
$1,090,989 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Spinal cord injury (SCI) often damages, not only white matter axon tracts that transmits signals to and from the brain, but also the central gray matter, causing segmental loss of interneurons and motor neurons. Transplantation of neural stem cells (NSCs) has the potential to replace lost neurons and glia. These transplanted neurons can form functional relays between spinal segments disconnected by the injury. We have generated human NSCs with a spinal cord identity to test the hypothesis that s... |