Funded Project Details - FY2021
|Title:|| Molecular Mechanisms of a Male-Specific Positive Feedback Loop in Liver Cancer|
Yun-Fai Chris Lau
||San Francisco, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| July 2019 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Hepatocellular carcinoma (HCC) is a deadly cancer that affects more Veterans than the general American population. Risk factors include hepatitis virus infection, obesity, aging, alcohol/drug abuses, toxic exposure, and genetic/epigenetic predisposition, which collectively promote genetic mutations, cell proliferation and signaling pathway dysfunctions, leading to cancer. Significantly, men are affected 3 to 6 times higher than women in HCC. The male predominance in HCC has been a long-standing...
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