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Funded Project Details - FY2021




Project Number:

I01BX004538-01A1
Title: Does Necroptosis Play a Role in Inflammation and Aging
Principal Investigator:

Arlan G. Richardson

Location: Oklahoma City, OK
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - September 2023
FY 2021 Funding Amount: $156,728
Total Award Amount
(all years):
$709,654
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Chronic, low-grade inflammation (inflammaging) is a hallmark of aging and is a major risk factor for both morbidity and mortality in the elderly humans. In addition, inflammation is a major risk factor for a variety of age-related diseases, e.g. type 2 diabetes, cardiovascular disease, cancer, neurodegenerative diseases, frailty, etc. Despite the link between inflammation, aging, and age-associated diseases, we do not know the molecular mechanism(s)/pathway(s) responsible for the chronic, low-gr...



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