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Project Number: | I01BX004666-01 |
| Title: | Targeting Molecular Transducers of Exercise for Osteoarthritis Therapies |
| Principal Investigator: | Timothy M Griffin |
| Location: | Oklahoma City, OK |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2019 - September 2023 |
| FY 2021 Funding Amount: | $256,002 |
| Total Award Amount (all years): |
$1,210,517 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Osteoarthritis (OA) disproportionately affects veterans, resulting in more pain and functional limitations compared to the general population. No disease-modifying treatments exist for OA, and current pain medications (e.g., opioids and NSAIDs) have limited long-term efficacy and adverse side effects. Unresolved cellular and molecular joint inflammation is recognized as the central mechanism of OA progression. However, a barrier to progress in the field is identifying the causes of chronic OA in... |