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Funded Project Details - FY2021




Project Number:

I01BX004707-01
Title: Molecular Repair of Diabetic Mesenchymal Stem Cells (dMSC) for Peripheral Arterial Disease
Principal Investigator:

Luke P Brewster

Location: Decatur, GA
Congressional District Code: 4
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$801,800
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Diabetes and peripheral arterial disease (PAD) disproportionately affect our nation's Veterans. Diabetic patients have limited collateralization and regenerative capacity in their tissues. Diabetic patients with peripheral arterial disease have severe ischemic complications and are at grave risk of major amputation. Reversing tissue ischemia by surgical revascularization prevents amputations, but many patients with diabetes and peripheral arterial disease are not fully treatable by surgical reva...



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