Office of Research & Development |
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Project Number: | I01BX004448-01A1 |
Title: | Hormonal control of NASH development and progression |
Principal Investigator: | Rhonda D. Kineman |
Location: | Chicago, IL |
Congressional District Code: | 7 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | April 2019 - March 2023 |
FY 2021 Funding Amount: | $156,800 |
Total Award Amount (all years): |
$852,637 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: SUMMARY/ABSTRACT Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of pathologies ranging from simple steatosis to non-alcoholic steatohepatitis (NASH – steatosis with hepatocellular injury) with or without fibrosis. NAFLD is prevalent in obese and diabetic patients, and represents an independent risk factor for cardiovascular disease and mortality. Within the VA patient population, the prevalence of obesity/diabetes/NASH is higher than in the general population and represents a ma... |