Funded Project Details - FY2021
|Title:|| Exploring Alzheimer Therapeutics|
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2020 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Abstract This project will advance the re-positioning of a novel therapeutic agent, fasudil, for the treatment of Alzheimer’s disease (AD). Currently there is a huge unmet need for safe and effective disease modifying therapies to treat and prevent AD. This study will generate preclinical pharmacological outcomes to prepare for the USA FDA application for AD clinical trials and extend our studies of the mechanism of action (MOA) of fasudil in cells and the 3X-Tg AD mouse model of disease. Both...
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