Office of Research & Development |
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Project Number: | IK2BX004585-01A1 |
Title: | Blocking lung cancer progression with peptide delivering cell therapy platforms |
Principal Investigator: | Richard T ONeil |
Location: | Nashville, TN |
Congressional District Code: | 5 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | July 2019 - June 2024 |
FY 2021 Funding Amount: | $207,196 |
Total Award Amount (all years): |
$1,050,845 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: For this project we propose to assess the utility of cell therapies for delivering the anti-cancer cytokines and chemokines in the context of non-small cell lung cancer models. Lung cancer is the leading cause of cancer related death in the Veteran population and metastasis is a major contributing factor to recurrence and mortality associated with non-small cell lung cancer. Aim 1 will take advantage TRAIL, a cytokine which induces apoptosis in cancer cells that is currently being evaluated as a... |