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Funded Project Details - FY2021

Project Number:

Title: Blocking lung cancer progression with peptide delivering cell therapy platforms
Principal Investigator:

Richard T ONeil

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: July 2019 - June 2024
FY 2021 Funding Amount: $207,196
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


For this project we propose to assess the utility of cell therapies for delivering the anti-cancer cytokines and chemokines in the context of non-small cell lung cancer models. Lung cancer is the leading cause of cancer related death in the Veteran population and metastasis is a major contributing factor to recurrence and mortality associated with non-small cell lung cancer. Aim 1 will take advantage TRAIL, a cytokine which induces apoptosis in cancer cells that is currently being evaluated as a...

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