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Funded Project Details - FY2021

Project Number:

Title: The role of eosinophils and oxidative stress in esophageal malignancy
Principal Investigator:

Yash Choksi

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2024
FY 2021 Funding Amount: $308,305
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The poor survival, high prevalence of smoking and alcohol use, and advanced stage at diagnosis of esophageal squamous cell carcinoma (ESCC) in the VA population necessitates further study into new management strategies for squamous cell carcinoma. Over the past few years, emerging immunotherapy approaches, such as adoptive cell transfer, have highlighted the importance of understanding and manipulating the tumor microenvironment. The tumor microenvironment in ESCC is understudied. In this propos...

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