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Funded Project Details - FY2021

Project Number:

Title: Low Molecular Weight Protein Nephrotoxicity
Principal Investigator:

Paul W. Sanders

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Clinical Science R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $154,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Multiple myeloma (MM) is a malignant plasma cell disorder that has an incidence rate of about 1.1% among all malignancies and constitutes 12-13% of hematologic malignancies in the US. The epidemiology is similar in our veteran population and includes a 3-fold higher prevalence of monoclonal gammopathy of undetermined significance, a premalignant lesion, in African American veterans. Renal dysfunction, determined by serum creatinine elevation ≥ 1.3 mg/dl, is frequently (about 48%) associated with...

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