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Project Number: | I01CX001326-05 |
| Title: | Low Molecular Weight Protein Nephrotoxicity |
| Principal Investigator: | Paul W. Sanders |
| Location: | Birmingham, AL |
| Congressional District Code: | 7 |
| Research Service: | Clinical Science R&D |
| Project Period: | October 2019 - September 2023 |
| FY 2021 Funding Amount: | $154,000 |
| Total Award Amount (all years): |
$709,612 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Multiple myeloma (MM) is a malignant plasma cell disorder that has an incidence rate of about 1.1% among all malignancies and constitutes 12-13% of hematologic malignancies in the US. The epidemiology is similar in our veteran population and includes a 3-fold higher prevalence of monoclonal gammopathy of undetermined significance, a premalignant lesion, in African American veterans. Renal dysfunction, determined by serum creatinine elevation ≥ 1.3 mg/dl, is frequently (about 48%) associated with... |