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Funded Project Details - FY2021

Project Number:

Title: Genetic Vulnerability for Sustained Multi-Substance Use in MVP
Principal Investigator:

Amy C. Justice

Location: West Haven, CT
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $156,371
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Harmful substance use (alcohol, tobacco, and/or prescription opioids) is common and twin studies suggest a substantial genetic role. Further, combined use of alcohol with tobacco and tobacco with opioids, commonly occurs suggesting that environmental and genetic risks for these behaviors overlap. However, identified genetic variation explains only a small proportion of the phenotypic variation for individual or combined substance use. Studies aiming to identify shared genetic pathways across sub...

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