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Project Number: | I01CX001904-01A1 |
| Title: | Validation of Mesoscopic Imaging to Predict Cutaneous Carcinogenesis and its Therapeutic Response |
| Principal Investigator: | Jeffrey B Travers |
| Location: | Dayton, OH |
| Congressional District Code: | 10 |
| Research Service: | Clinical Science R&D |
| Project Period: | October 2019 - September 2023 |
| FY 2021 Funding Amount: | $165,000 |
| Total Award Amount (all years): |
$709,625 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: PROJECT SUMMARY Actinic neoplasia (precancerous actinic keratosis and non-melanoma skin cancer) is the most common type of human neoplasia, and the most common diagnosis in VA dermatology clinics. We and other groups have characterized the mechanisms by which aging and ultraviolet B radiation (UVB) contribute to actinic neoplasia. In particular, human skin at high risk for actinic neoplasia exhibits biochemical features, including decreased keratinocyte expression of DNA repair enzymes, increase... |