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Funded Project Details - FY2021




Project Number:

I01CX001904-01A1
Title: Validation of Mesoscopic Imaging to Predict Cutaneous Carcinogenesis and its Therapeutic Response
Principal Investigator:

Jeffrey B Travers

Location: Dayton, OH
Congressional District Code: 10
Research Service: Clinical Science R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $165,000
Total Award Amount
(all years):
$709,625
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

PROJECT SUMMARY Actinic neoplasia (precancerous actinic keratosis and non-melanoma skin cancer) is the most common type of human neoplasia, and the most common diagnosis in VA dermatology clinics. We and other groups have characterized the mechanisms by which aging and ultraviolet B radiation (UVB) contribute to actinic neoplasia. In particular, human skin at high risk for actinic neoplasia exhibits biochemical features, including decreased keratinocyte expression of DNA repair enzymes, increase...



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