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Funded Project Details - FY2021




Project Number:

I01CX001971-01A2
Title: Immune control of chronic viral infection in solid organ transplantation
Principal Investigator:

Jonathan S. Maltzman

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Clinical Science R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $155,000
Total Award Amount
(all years):
$710,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Immunosuppression required for lifesaving solid organ transplantation induces significant morbidity including increased recurrence of latent viral infection in transplant recipients. Approximately 60-70% of adults in the United States are latently infected with Cytomegalovirus (CMV). Control of latent CMV is thought to depend on a constantly active immune response, specifically by memory T lymphocytes. In those with a normal immune system, control of latent CMV is a constant “battle” and results...



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