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Funded Project Details - FY2021

Project Number:

Title: Immune control of chronic viral infection in solid organ transplantation
Principal Investigator:

Jonathan S. Maltzman

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Clinical Science R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $155,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Immunosuppression required for lifesaving solid organ transplantation induces significant morbidity including increased recurrence of latent viral infection in transplant recipients. Approximately 60-70% of adults in the United States are latently infected with Cytomegalovirus (CMV). Control of latent CMV is thought to depend on a constantly active immune response, specifically by memory T lymphocytes. In those with a normal immune system, control of latent CMV is a constant “battle” and results...

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