Funded Project Details - FY2021
|Title:|| Immune control of chronic viral infection in solid organ transplantation|
Jonathan S. Maltzman
||Palo Alto, CA
|Congressional District Code:
||Clinical Science R&D
|| October 2019 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Immunosuppression required for lifesaving solid organ transplantation induces significant morbidity including increased recurrence of latent viral infection in transplant recipients. Approximately 60-70% of adults in the United States are latently infected with Cytomegalovirus (CMV). Control of latent CMV is thought to depend on a constantly active immune response, specifically by memory T lymphocytes. In those with a normal immune system, control of latent CMV is a constant “battle” and results...
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