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Project Number: | I01CX001761-01A2 |
| Title: | A pharmaco-imaging approach to predicting social functioning and clinical responses to oxytocin administration in schizophrenia |
| Principal Investigator: | Joshua Woolley |
| Location: | San Francisco, CA |
| Congressional District Code: | 12 |
| Research Service: | Clinical Science R&D |
| Project Period: | October 2019 - September 2024 |
| FY 2021 Funding Amount: | $285,604 |
| Total Award Amount (all years): |
$1,721,329 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Schizophrenia is a devastating illness that is characterized by deficits in social functioning. Social ability deficits, such as poor verbal and nonverbal social skills, negative symptoms, such as decreased motivation and emotional expressivity, and impaired theory of mind (ToM), the ability to understand the mental states of others, contribute to poor social functioning and are unresponsive to antipsychotic medications. Oxytocin (OT), a neuropeptide known to play a key role in social behavior,... |