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Funded Project Details - FY2021

Project Number:

Title: BLR&D Research Career Scientist Award Application
Principal Investigator:

Sebastian Joyce

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - March 2024
FY 2021 Funding Amount: $173,386
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The  overarching  goal  of  my  research  program  is  to  understand  the  molecular  mechanisms  of  immune  surveillance mediated by tissue-­resident memory T cells that patrol the mucosal barrier of the lungs to control  infectious diseases and cancers. My laboratory is best recognized for its contributions to the cell biology and  biochemistry  of  MHC  and  MHC-­like  CD1d  molecules.  These  molecules  play  important  roles  in  protein  and  lipid antigen presentation and, thereby, cont...

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