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Funded Project Details - FY2021

Project Number:

Title: Bioactive injectable implants for functional intervertebral disc regeneration
Principal Investigator:

Robert Mauck

Location: Philadelphia, PA
Congressional District Code: 3
Research Service: Rehabilitation R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $279,139
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Intervertebral disc degeneration is strongly implicated as a cause of low back pain. Over a 10 year period, more than 130,000 active service members received diagnoses of disc degeneration, with annual incidence rates more than doubling during this time. Current treatment approaches are mostly conservative, and in severe cases, patients may undergo surgical procedures such as spinal fusion, which do not maintain or restore native tissue structure or mechanical function. Mesenchymal stem cells (M...

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