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Funded Project Details - FY2021

Project Number:

Title: Early Visual Biomarkers of Relapse and Rehabilitation in Multiple Sclerosis
Principal Investigator:

Randy H. Kardon

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Rehabilitation R&D
Project Period: July 2019 - June 2023
FY 2021 Funding Amount: $300,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Optic neuritis is an associated pathology of MS, and is often the first symptom of the disease. Even in MS patients without any known episodes of optic neuritis, there is evidence that functional and structural manifestations of MS in the anterior visual pathway can be detected and monitored in vivo, reflecting disease activity. These include contrast sensitivity, critical flicker fusion frequency, evoked potentials from the retina and brain, and inner retinal layer thickness using optical coher...

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