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Funded Project Details - FY2021




Project Number:

I21RX003289-01
Title: Optimization of engineered endplates to improve in vivo integration of atissue engineered intervertebral disc
Principal Investigator:

Sarah E Gullbrand

Location: Philadelphia, PA
Congressional District Code: 3
Research Service: Rehabilitation R&D
Project Period: December 2019 - September 2022
FY 2021 Funding Amount: $47,427
Total Award Amount
(all years):
$155,110
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Low back pain, most commonly caused by degeneration of the intervertebral disc, places a significant social and economic burden on the general public, active duty military and veterans alike. Current clinical treatments for disc degeneration are limited in that they do not restore disc structure or function. To address this, our group has developed a whole, tissue engineered intervertebral disc composite (eDAPS) composed of engineered annulus fibrosus, nucleus pulposus and endplate regions. The...



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