Funded Project Details - FY2021
|Title:|| Neuron-targeted caveolin-1 as a gene therapy for ALS|
Brian P. Head
||San Diego, CA
|Congressional District Code:
|| January 2020 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease resulting from loss of both upper and lower motor neurons in the brain and spinal cord. ALS symptoms include diffuse muscle weakness, muscle atrophy, spasticity and hyperreflexia (upper), paralysis (lower), and 2-5 year life expectancy. One approach to combat ALS is delivery of neurotrophic factors to protect damaged motor neurons, but this is dependent upon expression and proper subcellular localization of key n...
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