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Funded Project Details - FY2021

Project Number:

Title: IL-1-based immunotherapy in HNSCC
Principal Investigator:

Andrean Burnett

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2021 Funding Amount: $232,064
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Immunotherapy-based strategies (i.e. anti-programmed cell death protein-1 (anti-PD1) are highly suitable options for VA patients given the more favorable toxicity profile compared to chemotherapy strategies and the remarkable durable tumor responses that can be triggered. However, only a minority of patients derive benefit from single-agent immunotherapies and improvements are needed before routine use of anti-PD1 agents as first-line treatment. Therefore there remains a significant need to iden...

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