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Funded Project Details - FY2021

Project Number:

Title: Investigating a novel regulatory pathway for opioid-induced synaptic plasticity and behavior
Principal Investigator:

John A. Wemmie

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The United States is in the midst of an opioid epidemic and risk is especially high in veterans. Current therapies consist mainly of alternative opioids, but their efficacy is limited. Thus, new treatments for pain and addiction are in high demand. Improved knowledge of the mechanisms underlying opioid addiction and relapse could help predict who might be a risk for addiction, and help to develop better therapies for those already battling addiction and relapse. The reinforcing effects of opioid...

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