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Funded Project Details - FY2021

Project Number:

Title: Microbiome and intestinal barrier in ALS therapy
Principal Investigator:

Jun Sun

Location: Chicago, IL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $240,266
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The goal of this application is to investigate the important role of intestinal microbial homeostasis in ALS, meanwhile investigating a novel approach that can potentially treat ALS by restoring host-microbe relationships and combining with FDA approved drugs. Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease characterized by progressive death of motor neurons and muscle atrophy. Most patients die within 5 years after the disease onset. Currently, treatment with Riluzole and R...

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