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Funded Project Details - FY2023

Project Number:

Title: Effect of Cyclical Intermittent Hypoxia on Lung Cancer Progression
Principal Investigator:

Diane C Lim

Location: Miami, FL
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2023 Funding Amount: $215,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Objective: Lung cancer continues to have a very poor prognosis, with Veterans having a higher incidence of lung cancer and worse outcome compared to civilians.1 Obstructive sleep apnea (OSA) has been associated with higher cancer incidence2-5 and mortality,2, 6-8 and again, Veterans have a higher prevalence of OSA that is more severe compared to civilians.9 Our overarching objective is to determine how cyclical intermittent hypoxia (CIH), a major underlying pathology of OSA, promotes lung cancer...

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