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Funded Project Details - FY2021

Project Number:

Title: Determining the value of PBP 7/8 as an antimicrobial target for XDR-A. baumannnii
Principal Investigator:

Thomas A. Russo

Location: Buffalo, NY
Congressional District Code: 26
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2024
FY 2021 Funding Amount: $120,049
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Anticipated Impacts on Veterans Health Care. The incidence of infections due to highly resistant Acinetobacter baumannii is increasing. True pan drug resistant (PDR) strains have been reported. Unfortunately, the newly approved antimicrobials ceftolozane-tazobactam, ceftazidime-avibactam, and meropenem/vaborbactam are poorly active against resistant A. baumannii. The need to identify new antimicrobials active against A. baumannii is pressing. Background. We have demonstrated that the A. baumanni...

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