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Project Number: | I01BX004677-01A1 |
| Title: | Determining the value of PBP 7/8 as an antimicrobial target for XDR-A. baumannnii |
| Principal Investigator: | Thomas A. Russo |
| Location: | Buffalo, NY |
| Congressional District Code: | 26 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2019 - September 2024 |
| FY 2021 Funding Amount: | $120,049 |
| Total Award Amount (all years): |
$699,241 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Anticipated Impacts on Veterans Health Care. The incidence of infections due to highly resistant Acinetobacter baumannii is increasing. True pan drug resistant (PDR) strains have been reported. Unfortunately, the newly approved antimicrobials ceftolozane-tazobactam, ceftazidime-avibactam, and meropenem/vaborbactam are poorly active against resistant A. baumannii. The need to identify new antimicrobials active against A. baumannii is pressing. Background. We have demonstrated that the A. baumanni... |