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Funded Project Details - FY2021




Project Number:

I01BX004729-01A1
Title: PROBING THE CELL-SPECIFIC CONTROL OF FOCAL CORTICAL SEIZURE EVENTS IN VIVO
Principal Investigator:

Stelios Smirnakis

Location: Boston, MA
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2021 Funding Amount: $141,773
Total Award Amount
(all years):
$649,711
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

    Epilepsy  is  a  common  severe  neurological  disorder  with  one-­year  prevalence  ~7/1,000,  whose  circuit  mechanisms  are  poorly  understood.  Its  prevalence  is  high  among  veterans.  Patients  with  post-­traumatic  brain  injury  carry  a  high  risk  of  epilepsy  for  decades  following  injury,  causing  considerable  morbidity.  At  15  years  following  injury  51%  of  the  subjects  in  the  Vietnam  Head  Injury  Study  carried  a  diagnosis  of  seizure.  Clearly  epi...



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