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Funded Project Details - FY2021

Project Number:

Title: Mechanisms of synergistic regulation of biliary inflammation and fibrosis
Principal Investigator:

Heather Lee Francis

Location: Indianapolis, IN
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The risk of liver diseases due to alcohol and toxin abuse and hepatitis viruses in US Veterans is increasingly high and is one of the most common reasons for hospitalization and mortality. Hepatic fibrotic disease represents one of the largest groups of disorders for which there is no effective therapy and thus denotes a major unmet medical need. Often the only option for patients with liver fibrosis is organ transplantation. Chronic liver diseases include cholangiopathies that target cholangioc...

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