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Funded Project Details - FY2021

Project Number:

Title: The Multiple Roles of Lysyl Oxidase in Arteriovenous Fistula Failure
Principal Investigator:

Roberto Vazquez-Padron

Location: Miami, FL
Congressional District Code: 24
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $239,648
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


More than 14 000 enrolled veterans depend on an arteriovenous (A-V) fistula or other type of vascular access to receive hemodialysis and prolong their lives. The transformation of a vein to a fistula is one of the most intriguing processes in vascular biology. The desired scenario is that the fistula matures becoming a larger vessel with increased luminal area and a thicker wall. Unfortunately, A-V fistulas frequently fail (~40%) because venous stenosis compromises blood flow. We recently discov...

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