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Project Number: | I01BX004921-01 |
| Title: | Role of EPAC Signaling in Melanoma Progression |
| Principal Investigator: | Vijayasaradhi Setaluri |
| Location: | Madison, WI |
| Congressional District Code: | 2 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2019 - September 2023 |
| FY 2021 Funding Amount: | $272,424 |
| Total Award Amount (all years): |
$1,289,274 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: ABSTRACT Cutaneous melanoma arises from melanocytes in the skin. Exposure to solar ultraviolet (UV) radiation is a significant risk factor. Deployment of US military personnel around the world in areas of high UV index thus increases risk of melanoma during and after military service. If diagnosed early, excision of the primary tumor in the skin can be curative. However, the five-year survival rates decrease precipitously as melanoma metastasizes to local and regional lymph nodes and distant org... |