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Project Number: | I01BX004868-01 |
| Title: | 5-HT1F receptor agonism as a novel therapeutic strategy following spinal cord injury |
| Principal Investigator: | Rick Schnellmann |
| Location: | Tucson, AZ |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | November 2019 - October 2023 |
| FY 2021 Funding Amount: | $257,005 |
| Total Award Amount (all years): |
$1,168,584 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The goal of this project is to study the 5-hydroxytryptamine 1F (5-HT1F) in stimulating mitochondrial biogenesis (MB) and recovery from spinal cord injury (SCI). SCI is a devastating disorder often resulting in loss of function below the injury site. While combat-related spinal trauma has been documented for centuries, in recent years, service members have been threatened by more advanced warfare, such as rocket-propelled grenades and improvised explosive devices, ultimately inducing more severe... |