Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021




Project Number:

IK2BX004909-01
Title: Enteroendocrine cell reprogramming during intestinal injury
Principal Investigator:

Brian Muegge

Location: St Louis, MO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: February 2020 - January 2025
FY 2021 Funding Amount: $148,084
Total Award Amount
(all years):
$1,140,543
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

RESEARCH STRATEGY: The primary research objective of this proposal is to address how subtypes of enteroendocrine cells change their activity (secretion) or state of differentiation in response to injury signals. A better understanding of intestinal injury repair is critical to VA health priorities; the prevalence of inflammatory bowel disease (IBD) has more than doubled among VA patients since 1998 and at least half of patients won’t experience full mucosal healing with existing therapies. Hormo...



Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.