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Funded Project Details - FY2021




Project Number:

IK2BX004885-01
Title: The role of enterocyte apical structure in inflammatory bowel disease pathogenesis
Principal Investigator:

Leslie Meenderink

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2025
FY 2021 Funding Amount: $225,733
Total Award Amount
(all years):
$1,315,933
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

PROJECT SUMMARY Inflammatory bowel disease (IBD), comprised of Crohn’s disease and Ulcerative colitis, is a chronic relapsing disorder that affects 1.4 million Americans including an estimated 600 per 100,000 veterans causing malabsorption, bloody diarrhea, strictures, fistulas, and infection. In addition, the chronic inflammatory state increases the risk for colorectal cancer with poorer prognosis and reduced survival rates compared to non-IBD patients. Immunotherapy is increasingly effective;...



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