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Funded Project Details - FY2023

Project Number:

Title: Advancing Non-Invasive Diagnostics and Treatments of Deployment-Related Chronic Lung Disease in Gulf War Veterans
Principal Investigator:

John J Osterholzer

Location: Ann Arbor, MI
Congressional District Code: 12
Research Service: Biomedical Laboratory R&D
Project Period: July 2020 - June 2024
FY 2023 Funding Amount: $237,217
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Rationale. An increased incidence of respiratory complaints has been identified in Veterans of the Gulf War (GW) [and post-9/11 conflicts. An inhalational injury is suspected given numerous potential exposures to airway toxins. A landmark study (1) in 2011 described a cohort of post-9/11 soldiers with unexplained dyspnea and impaired exercise tolerance that underwent surgical lung biopsy; findings showed evidence of chronic inflammation surrounding thickened fibrotic bronchioles referred to as d...

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